Maclaran & Panay, 2012
This review examines one of the most important questions in women’s hormone therapy: safety. Maclaran and Panay analyze the available evidence on postmenopausal testosterone therapy with a focus on breast, endometrial, and cardiovascular outcomes. Their review highlights that much of the concern surrounding testosterone in women has outpaced the evidence, and that when used in physiologic doses, testosterone therapy may offer meaningful benefit while requiring thoughtful clinical oversight and continued long-term study. (Europe PMC)
In short: this paper is often cited because it reviews the evidence on breast, endometrial, and cardiovascular safety and helps explain why physiologic testosterone therapy in postmenopausal women may be safer than many assume.


